ISTA Pharmaceuticals, Inc. is a rapidly growing ophthalmic pharmaceutical company based in Irvine, California. As of July 2009, ISTA was the fourth largest branded ophthalmic pharmaceutical business in the U.S., according to data provided by IMS Health.

ISTA currently markets four products in the United States: Bepreve™ (bepotastine besilate ophthalmic solution) 1.5% for the treatment of itching associated with signs and symptoms of allergic conjunctivitis, Xibrom™(bromfenac ophthalmic solution) 0.09% for the treatment of inflammation and pain following cataract surgery, Istalol^® (timolol maleate ophthalmic solution) 0.5% for the treatment of glaucoma, and Vitrase^® (hyaluronidase injection) Ovine, 200 USP Units/mL for use as a spreading agent. ISTA also has several allergy and eye product candidates in various stages of development.